ÿþ <!doctype html public "_//w3c//dtd html 4.01 frameset//en"> <html> <head><title>Dr.Muranyi Website</title> <script src="rollover.js" type="text/javascript"></script> <link rel="stylesheet" type="text/css" href="webmarian.css"> <meta http-equiv="content-type" content="text/html; chareset="iso-8859-1"> <META HTTP-EQUIV="Last-Modified" CONTENT="20 March 2008"> <META NAME="ROBOTS" CONTENT="index"> <META NAME="description" CONTENT=" science"> <META NAME="keywords" CONTENT="science, biomedical research, diseases, biotech"> <META name="abstract" content="Dr.Marianna Muranyi"> <META name="copyright" content="Copyright © Marianna Muranyi. All rights reserved."> <META name="distribution" content="global"> <META HTTP-EQUIV="content-language" CONTENT="EN"> </head> <p><blockquote> <TABLE WIDTH="1000" height="" VALIGN=middle ALIGN=center BORDER="0" BORDERCOLOR="#25B0AD" CELLPADDING="0" CELLSPACING="0" background=".jpg" width="300" height="299"> <TR> <td colspan="3" width="" height="30" align="center" valign="top"> <br><br><br><br><br><br><br><br> <!--menu sor kezdete--> <span class="menu"><a href="index.html" target="" style="text-decoration:none">&nbsp;&nbsp;&nbsp;HOME&nbsp;&nbsp;&nbsp;</a></span> <span class="menu"><a href="us.html" target="" style="text-decoration:none">&nbsp;&nbsp;&nbsp;ABOUT US&nbsp;&nbsp;&nbsp;</a></span> <span class="menu"><a href="kcenter.html" target="" style="text-decoration:none">&nbsp;&nbsp;&nbsp;KNOWLEDGE CENTER&nbsp;&nbsp;&nbsp;</a></span> <span class="menu"><a href="contact.html" target="" style="text-decoration:none">&nbsp;&nbsp;&nbsp;CONTACT&nbsp;&nbsp;&nbsp;</a></span> </td> </tr> <!--menu table vege --> <blockquote> <!--tartalom kezdete --> <tr> <td width="150" height="" ></td> <td width="" height="" align="justify" valign="top" border="0"> <font size="5"> <center><br><bold>MedScience Center</font></center> <font size="4"> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; ... is an ultimate information center in biomedical research providing expansive information for biomedical scientists and investors. Useful links to science jobs, grant opportunities, worldwide universities and organizations. Infos on investing into biotech companies. Infos about actual biomedical research topics. Introduction of great scientists and histories of science. <br><br> </td> <td width="150" height="" ></td> </tr> <tr> <td colspan="3" width="1000" height="600" align="justify" valign="top" border="0"> <font size="4"> <blockquote> <img src="images/mmszines.jpg" width="160" height="200" align="left" hspace="15" vspace="15"> <br> Director: Marianna Muranyi, Ph.D. <br><br> Curriculum Vitae summary <br> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; I have been conducting biomedical research since 1999. I started my research on opioid addiction at the Biological Research Center of the Hungarian Academy of Science and got my M.S. degree from biology at the University of Szeged in 2001 in Hungary. I continued biomedical research on ischemic cerebral injury at the University of Hawai'i in the USA between 2001-2005 which work was summarized in my Ph.D. thesis. Before my Ph.D. defense I spent one year at Semmelweis University in Hungary involved in projects including diabetes mellitus and stem cell research. In 2006, I got my Ph.D. degree in Basic Medical Sciences. Afterwards, I continued medical research at New York University on the molecular mechanisms of Alzheimer s disease and memory functions. Then, I worked as a science liaison for a biotech company recruiting biomedical research partners in Hungary who have novel concepts and technologies to bring to the US research and development market. Beyond my scientific activities, I also teach and introduce research to undergraduate and graduate students and convey information about science topics to the public. My scientific interest encompasses many areas of neuroscience and molecular biology <a href="resint.html" target="" >(see details)</a>. <br><br><br> <b><center>Education</center></b> <br> Ph.D. 2006, Semmelweis University, Ph.D. School for Basic Medical Sciences, Budapest, Hungary<br><br> M.S. 2001, University of Szeged, Faculty of Natural Sciences, Major in Biology, Specialized in Neurobiology and Cell Biology, Szeged, Hungary<br><br> M.Ed. 2001, University of Szeged, Major in Education, Szeged, Hungary <br> <br> <br> <b><center>Professional experience</center></b> <br> Research Specialist, 2010-present, University of Hawaii, Cancer Research Center, Honolulu, HI <br><br> Collaborative Scientist, 2009-2010, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary <br><br> Science Journalist, 2009-present <br><br> Scientific Advisor, 2007-2010, BioMedTek. Ltd., Pecs, Hungary <br><br> Assistant Research Scientist, 2006-2007, New York University, Center for Neural Science, New York, NY <br><br> Research Assistant, 2005-2006, Semmelweis University, Institute of Clinical Experimental Research and Human Physiology, Budapest, Hungary <br><br> Research Scholar, 2001-2005, University of Hawaii at Manoa, Cardiovascular Research Center, Honolulu, HI <br><br> Undergraduate Researcher, 1998-2001, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary <br><br> <br> <b><center>Publications</center></b> <br> <font size="4"> Eszter Pankotai, Zsombor Lacza, <b>Marianna Muranyi</b>, Márk Kollai, Csaba Szabó. Poly-ADP-ribosylation in mitochondria - possible role for the alpha-ketoglutarate dehydrogenase. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19460292">Mitochondria.</a> <br> <br> Horváth EM, BenkQ R, Kiss L, <b>Murányi M</b>, Pék T, Fekete K, Bárány T, Somlai A, Csordás A, Szabo C. Rapid 'glycaemic swings' induce nitrosative stress, activate poly(ADP-ribose) polymerase and impair endothelial function in a rat model of diabetes mellitus. <a href="http://www.ncbi.nlm.nih.gov/pubmed/19263033?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">Diabetologia.</a> <br> <br> Attila Keresztes, Mária Szqcs, Attila Borics, Katalin E. Kövér, EnikQ Forró, Ferenc Fülöp, Csaba Tömböly, Antal Péter, Annamária Páhi, Gabriella Fábián, <b>Marianna Murányi</b>, Géza Tóth. New Endomorphin Analogs Containing Alicyclic ²-Amino Acids: Influence on bioactive conformation and pharmacological profile. <a href="http://www.ncbi.nlm.nih.gov/pubmed/18572932?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">J Med Chem. 24;51(14):4270-9, 2008</a> <br> <br> R. Laczko, P. Hollosi, K. M. Szauter, M. K. Jansen, <b>M. Muranyi</b>, J. Molnar, K. S. K. Fong, A. Hinek and K. Csiszar. Lysyl oxidase (LOX) promotes focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes. <a href="http://www.ncbi.nlm.nih.gov/pubmed/17931358?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">Neuropathology and Applied Neurobiology, 33(6):631-43, 2007</a> <br> <br> <b>Marianna Muranyi</b>. Influence of diabetes mellitus on cerebral ischemia and reperfusion injury. Ph.D. thesis. Budapest, Hungary, 2006</a> <br> <br> <b>Marianna Muranyi</b>, Chaonan Ding, QingPing He, Yanling Lin and Ping-An Li: Streptozotocin-induced diabetes causes astrocyte death after ischemia and reperfusion injury. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16443767&query_hl=2&itool=pubmed_docsum" target="new">Diabetes, 55(2):349-55, 2006</a> <br> <br> <b>Marianna Muranyi</b>, and Ping-An Li: Hyperglycemia increases superoxide production in the CA1 pyramidal neurons after global cerebral ischemia. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16257122&query_hl=2&itool=pubmed_docsum"target="new">Neurosci Lett, 393(2-3):119-21, 2006</a> <br> <br> <b>Marianna Muranyi</b>, QingPing He, Keith S. K. Fong and Ping-An Li: Induction of heat shock proteins by hyperglycemic cerebral ischemia. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15961182&query_hl=2&itool=pubmed_docsum"target="new">Brain Res Mol Brain Res, 139(1):80-7, 2005</a> <br> <br> <b>Marianna Muranyi</b>, Ping-An Li: Bongkrekic acid ameliorate ischemic neuronal death in the cortex by preventing cytochrome c release and inhibiting astrocyte activation. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15919152&query_hl=2&itool=pubmed_docsum"target="new">Neurosci Lett, 384(3):277-81, 2005</a> <br> <br> <b>Marianna Muranyi</b>, Masayuki Fujioka, QingPing He, Angela Han, Gregory Yong, Katalin Csiszar, Ping-An Li: Diabetes activates neuronal cell death pathway after focal cerebral transient ischemia. <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12540624&query_hl=2&itool=pubmed_docsum"target="new">Diabetes, Vol.52:481-486, 2003</a> <br> <br> Marianna Muranyi. In vitro and in vivo study of endomorphine analogs. MS thesis in Neuropharmacology, Szeged, Hungary, 2001 <br><br><br> <font size="4">Under preparation</font> <br><br> Marianna Murányi, Géza Tóth, Mónika Mácsai, Gyula Szabó, Mária Szqcs. Lack of internalization following chronic treatment of a full agonist endomorfin-2 analogue. <br> <br> Attila Csordás, Zsófia Szabó, Gábor Orosz, <b>Marianna Muranyi</b>, Zsófia Kovács, Attila Cselenyák, Ferenc Uher, Márk Kollai, Csaba Szabó, Zsolt Radák, Zsombor Lacza. Bone marrow derived stem cells integrate into red muscle fibers and improve training performance in rats undergoing physical exercise. <br><br><br> <b><center>Reviews and other publications</center></b> <br> <b>Marianna Muranyi</b>, Zsombor Lacza: Influence of diabetes mellitus on cerebral ischemia and reperfusion injury. (Review) <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17111650&query_hl=2&itool=pubmed_docsum" target="new">Hungarian Medical Journal, 147(39):1885-9, 2006</a> <br> <br> <b>Marianna Muranyi</b>, Zsombor Lacza: Astrocytes in health and disease. (Review) <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17416578&query_hl=1&itool=pubmed_docsum" target="new"> Hungarian Medical Journal, 148(15):697-702, 2007</a> <br> <br> <b>Marianna Muranyi</b>, Zsolt Radak: Pain and opioids. (Review) <a href="http://www.ncbi.nlm.nih.gov/pubmed/19073443?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum">Hungarian Medical Journal. 14;149(50):2363-70, 2008</a> <br> <br> Marianna Muranyi. Stress-induced posttranslational modification of proteins, lipids and nucleic acids. Biochemisty. (Article in Hungarian) 13(2), 2009 <br> <br> Marianna Muranyi. How to alleviate pain? Causes and treatments. Life and Science. (Educational article in Hungarian) 24/2009 <br> <br> Marianna Muranyi. Vaccines and germs. Defence with help. Life and Science. (Educational article in Hungarian) 28/2009 <br> <br> Marianna Muranyi. Contaminated water and food. Life and Science. (Educational article in Hungarian) 38/2009 <br> <br> Marianna Muranyi. Germs transmitted by insects. Life and Science. (Educational article in Hungarian) 41/2009 <br> <br> Marianna Muranyi. DNA testing. Life and Science. (Educational article in Hungarian) 10/2010 <br> <br> Marianna Muranyi. Blood testing. Life and Science. (Educational article in Hungarian) /2010 <br> <br> </font> </td> </TR> </table> </body>